Loni Anderson, the iconic actress best known for her role in ‘WKRP in Cincinnati,’ has died from metastatic uterine leiomyosarcoma, a rare and aggressive form of cancer, as confirmed by her death certificate. This revelation has brought closure to fans and the entertainment industry, highlighting her battle with a prolonged illness.
Loni Anderson was a celebrated American actress who gained fame in the late 1970s and early 1980s for her portrayal of Jennifer Marlowe on the popular sitcom ‘WKRP in Cincinnati.’ Her career spanned decades, including film roles and high-profile personal relationships, making her a beloved figure in Hollywood.
The cause of her death was metastatic uterine leiomyosarcoma, which is an extremely rare cancer that often originates in the uterus and can spread to other parts of the body. This diagnosis was detailed in her death certificate, obtained exclusively by TMZ, providing official confirmation after initial reports of her passing.
Anderson died on August 3, 2025, at the age of 79, just days before what would have been her 80th birthday. The news of her cause of death was made public on August 22, 2025, through various media outlets, bringing renewed attention to her final days.
She passed away at a hospital in Los Angeles, California, where she had been receiving treatment for her illness. Her longtime publicist, Cheryl J. Kagan, described it as a ‘prolonged’ illness, indicating a struggle with health issues leading up to her death.
The reason for her death was the aggressive nature of the cancer, which is known for its rarity and difficulty in treatment. Uterine leiomyosarcoma accounts for a small percentage of uterine cancers and often has a poor prognosis, especially when metastatic.
The information was revealed through the death certificate, which was accessed by TMZ, and corroborated by other news sources like Deadline and Fox News. This official document provided the definitive cause, ending speculation and allowing for accurate reporting.
Her death has had a significant impact on the entertainment community and her fans worldwide, prompting an outpouring of grief and tributes. Colleagues, such as Barbara Eden from ‘I Dream of Jeannie,’ expressed sadness and praised Anderson’s kindness and legacy as a mother and actress.
Looking ahead, Anderson’s contributions to television and film will be remembered through retrospectives, memorials, and ongoing appreciation of her work. Her role in ‘WKRP in Cincinnati’ remains a cultural touchstone, ensuring her place in entertainment history.